Antibodies
Software
- KabatMan is a database program for accessing the computerised version of the Kabat sequence database maintained by George Johnson and Tai Te Wu. It uses an SQL-like query language, the exception being that clauses are joined in Reverse Polish Notation. One day, this might be changed to ordinary infix notation, but it's not a priority since RPN is straightforward once you get used to it. Click here for further information. You may query the KabatMan database from the WWW using a point and click interface or using the KabatMan query language.
- AbM is Oxford Molecular Ltd.'s antibody modelling package based on algorithms developed by me and members of Tony Rees's group at Bath University as well as by Bob Bruccoleri and Cyrus Chothia. N.B. This is a commercial package. Unfortunately, since Oxford Molecular was taken over by Accelrys, AbM is no longer available.
- WAM is an update to AbM from Whitelegg and Rees, accessible over the web. The method is described in the paper Whitelegg and Rees (2000), "WAM: an improved algorithm for modelling antibodies on the Web", Protein Engineering 13, 819-824. Access to WAM is free of charge for academics. Access WAM at http://antibody.bath.ac.uk/
Our other software is accessible from the Sequences page of this web site.
