Group

Current members

 

Group photo

Left-to-right: Abhi, Craig, Lisa, Jake, Andrew, Sri

PhD students

Anja Baresic is examining the structural effects of mutations in 'compensated pathogenic deviations' and developing methods to prediction residues involved in protein-protein interactions and therefore sensitive to mutations. (2007-2011)

Nouf Alnumair is working on looking at mutation data in SAAPdb where there are multiple structures available and the sensitivity of the analyses to detail of the structure. This will then move on to look at modelled structures and which analyses can be applied to them. (2009-)

Narayan Jayaram is working on looking at the effects of mutations at the DNA level (i.e. effects on splice sites and transcription factor binding sites) and integrating this into SAAPdb.

PhD rotation students

Stuart Tetchner is a Wellcome Trust rotation student jointly supervised by Steve Perkins working on predicting zinc binding sites in complement proteins.

Visitors / Interns

Pawan Shree Poudel is a summer intern building a new web server to run our analysis tools on the effects of mutations, providing both a visual web site and RESTful web services.

Undergraduate project students

Joseph Replogle is looking at clustering of mutations in protein structures (2011-2012)

Tarit Puvanuttrai is working on GroEL-dependent proteins (2011-2012)

Catherine Orr and Jennifer Dhingra are doing literature projects on the TGN1412 drug trial (2011-2012)

MSc/MRes project students

Nick Tu is working on analysis of luciferase strcuture with a view to modifying its specificity