www.bioinf.org.uk : Dr. Andrew C.R. Martin's Group
Left-to-right: Abhi, Craig, Lisa, Jake, Andrew, Sri
Anja Baresic developing and enhancing an HMM-based algorithm for identifying conserved regions in proteins and applying this to prediction of residues involved in functional interactions and therefore sensitive to mutations. (2007-)
Irena Sani is working on interactions of RNA (2008-)
Nouf Alnumair is working on looking at mutation data in SAAPdb where there are multiple structures available and the sensitivity of the analyses to detail of the structure. This will then move on to look at modelled structures and which analyses can be applied to them. (2009-)
Chris Fu is working on modelling the mTOR protein (Spring 2010)
None at present.
Calum Smith will be doing a literature project looking at effects of mutations on protein structure and function together with a full comparison of the different available resources and methods that analyze mutation data and perform predictions.
Ross Kruger will be examining variation in packing quality in protein structures to investigate whether there is any link with function, or evolution. Primarily the project will use our AVP software to analyze the packing quality.
Minu Bhatt is a Birkbeck MSc student looking at analysis and prediction of ubiquitination sites. (2010)
Palab Bhowmick and Narayan Jayaram are Birkbeck MSc students looking at preferred pairing of antibody germline sequences using Abysis. (2010)
Peter Halls is a Birkbeck MSc student evaluating the performance of out mutmodel program for sidechain replacement. (2010)