Servers

Most of the servers we provide are linked to from other parts of the site, but this page summarizes the links to those and also includes some other facilities that we make available.

Follow the tabs above, or the links below to access the various servers.

Antibodies

Analysis of antibody sequence and structure

Abysis	New integrated database of antibody sequence and structure
KabatMan	Point-and-click interface to KabatMan
KabatMan	Full query interface to KabatMan
SeqTest	Check your antibody sequence for unusual features
Chothia Canonicals	Identify canonical conformations for CDRs for your antibody sequence
Human subgroups	Identify subgroups for your human antibody sequence
SHAB	Assess humanness of an antibody sequence
SACS	Automatically maintained database of antibody structures in the PDB
AbNum	Automatically apply numbering to an antibody sequence

Mutations

Analysis of structural and disease effects of mutations

CheckHBond	Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility. Can be used when examining mutations to see whether hydrogen bonds are maintained
SAAP Database	Query our database of SNP data
G6PD Database	Query our database of mutations in G6PD
OMIM Missense Mutations	Query our database of missense mutations extracted from OMIM with validated residue numbers of mutations sites in SwissProt
3DSim	Integration of SAAPdb with Gene3D and CATH

Protein structure and sequence

Tools for analysis of protein structure (rapid structure comparison, mappings to UniProt and EC numbers, analysis of hydrogen bonds) and sequence (orthologous groups, annotation)

FOSTA	Database of functionally-equivalent proteins, i.e. groups of orthologous proteins extracted from SwissProt which perform the same function in different species. (This is the new name for Orthofind.)
CheckHBond	Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility
PDBSprotEC	Link PDB protein chains to SwissProt entries and EC numbers
PDBSWS	Comprehensive mapping of PDB protein chains to SwissProt entries
TopScan	Rapid approximate comparison of a structure against structures in the PDB
APAT	Automated Protein Annotation Tool
ImPACT	Improved Protein Alignment Conservation Threshold - Takes a sequence alignment and provides a threshold for considering a residue to be 'highly conserved'
ProFit	A simple interface for using the basic features of ProFit over the web.

Miscellaneous

Other tools

PubMed

Tools for PubMed literature searching