www.bioinf.org.uk : Dr. Andrew C.R. Martin's Group
Most of the servers we provide are linked to from other parts of the site, but this page summarizes the links to those and also includes some other facilities that we make available.
Follow the tabs above, or the links below to access the various servers.
Analysis of antibody sequence and structure
| KabatMan | Point-and-click interface to KabatMan |
| KabatMan | Full query interface to KabatMan |
| SeqTest | Check your antibody sequence for unusual features |
| Chothia Canonicals | Identify canonical conformations for CDRs for your antibody sequence |
| Human subgroups | Identify subgroups for your human antibody sequence |
| SHAB | Assess humanness of an antibody sequence |
| SACS | Automatically maintained database of antibody structures in the PDB |
Analysis of structural and disease effects of mutations
| CheckHBond | Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility. Can be used when examining mutations to see whether hydrogen bonds are maintained |
| SAAP Database | Query our database of SNP data |
| G6PD Database | Query our database of mutations in G6PD |
| OMIM Missense Mutations | Query our database of missense mutations extracted from OMIM with validated residue numbers of mutations sites in SwissProt |
Tools for analysis of protein structure (rapid structure comparison, mappings to UniProt and EC numbers, analysis of hydrogen bonds) and sequence (orthologous groups, annotation)
| FOSTA | Database of functionally-equivalent proteins, i.e. groups of orthologous proteins extracted from SwissProt which perform the same function in different species. (This is the new name for Orthofind.) |
| CheckHBond | Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility |
| PDBSprotEC | Link PDB protein chains to SwissProt entries and EC numbers |
| PDBSWS | Comprehensive mapping of PDB protein chains to SwissProt entries |
| TopScan | Rapid approximate comparison of a structure against structures in the PDB |
| APAT | Automated Protein Annotation Tool |
Other tools
| PubMed | Tools for PubMed literature searching |
PDBSprotEC now contains many more mappings as EC numbers are now gather from trEMBL as well as from SwissProt. Links to external servers have also been fixed.
FOSTA allows you to identify groups of orthologous proteins from UniProtKB/SwissProt which perform the same function in different species. (This is the new name for Orthofind.)