Mutations

We are interested in the effects of mutations on protein structure and function.

In particular we have worked on the analysis of the local structural effects of mutations on p53 and G6PD. We are currently expanding this analysis to encompass all mutation and structure data we can obtain in an automated fashion.

Please follow the links in the menu on the left of this page to explore our work in this area.





Availability

25.02.14 APOLOGIES! We are still finding problems resulting from our web server faiing over the Christmas break. The SACS database and ImPACT are now fully available again!

18 October 2014

Two new pieces of software to help programmers: JSAV, a JavaScript Sequence Alignment Viewer component for web sites; BiopLib, 25 years worth of C code development for handling (mostly) protein structure.