This page provides supporting material for our paper on Compensated Pathogenic Mutations:
Baresic, A. McMillan, L.E.M., Rogers, H.H., Hurst, J.M. and Martin, A.C.R (2010) Compensated pathogenic deviations: analysis of structural effects, Journal of Molecular Biology, 396, 19-30. DOI: http://dx.doi.org/10.1016/j.jmb.2009.11.002
The CSV file and HTML table contain the following columns:
| 1 | Native | The native human amino acid |
| 2 | Human Position | The sequential residue number in the human SwissProt sequence |
| 3 | Mutant | The human mutant known to cause disease |
| 4 | Human AC | The SwissProt accecssion code for the human sequence |
| 5 | Non-Human AC | The SwissProt accession code for the non-human sequence |
| 6 | Non-Human Position | The sequential residue number in the non-human SwissProt sequence |
- Table of CPD mutations with structures [HTML] [CSV]
- Table of PD mutations with structures [HTML] [CSV]
The CSV files and HTML tables contain the following columns:
| 1 | Human AC | The SwissProt accecssion code for the human sequence |
| 2 | Native | The native human amino acid |
| 3 | Human Position | The sequential residue number in the human SwissProt sequence |
| 4 | Mutant | The human mutant known to cause disease |
| 5 | PDB code | The PDB code for the structure used in analysis |
| 6 | PDB chain | The PDB chain identifier for the structure used in analysis |
| 7 | PDB resnum | The PDB residue number for the structure used in analysis |