bioinf.org.uk - Prof. Andrew C.R. Martin's group at UCL

CPD Mutations with structures

HumanAC	Native	SprotNum	Mutant	PDBCode	PDBChain	PDBNum
O96017	ARG	181	CYS	1gxc	J	181
O96017	GLU	239	LYS	2cn5	A	239
P00325	ARG	48	HIS	1u3u	A	47
P00439	ARG	176	LEU	1j8u	A	176
P00439	ARG	261	GLN	1j8u	A	261
P00439	ASP	415	ASN	1j8u	A	415
P00439	PRO	407	LEU	1j8u	A	407
P00441	ALA	5	VAL	1mfm	A	4
P00441	ASP	91	ALA	1mfm	A	90
P00441	ASP	97	ASN	1mfm	A	96
P00441	GLU	22	LYS	1mfm	A	21
P00441	GLY	94	CYS	1mfm	A	93
P00441	HIS	44	ARG	1mfm	A	43
P00441	HIS	81	ALA	1mfm	A	80
P00441	LEU	107	VAL	1mfm	A	106
P00480	ARG	129	HIS	1oth	A	129
P00480	LEU	148	PHE	1oth	A	148
P00480	LYS	46	ARG	1oth	A	46
P00480	PRO	225	LEU	1oth	A	225
P00488	VAL	35	LEU	1ex0	B	34
P00492	GLY	16	SER	1z7g	A	15
P00492	LEU	78	VAL	1z7g	B	77
P00492	SER	110	LEU	1bzy	A	109
P00492	THR	168	ILE	1z7g	D	167
P00918	ASN	252	ASP	1lug	A	252
P00966	ARG	108	LEU	2nz2	A	108
P00966	GLY	390	ARG	2nz2	A	390
P00995	ASN	34	SER	1hpt	A	11
P01008	ALA	419	VAL	2b5t	I	387
P01008	SER	323	PRO	2b5t	I	291
P01009	ARG	125	HIS	1qlp	A	101
P01009	ASP	365	ASN	1qlp	A	341
P01009	GLU	228	LYS	1qlp	A	204
P01009	GLU	400	ASP	1qlp	A	376
P01009	GLY	139	SER	1qlp	A	115
P01009	GLY	172	ARG	1qlp	A	148
P01009	LEU	377	PHE	1qlp	A	353
P01116	ALA	59	THR	1d8d	A	219
P01116	GLY	12	SER	1d8d	A	172
P01116	GLY	12	VAL	1d8d	A	172
P01308	HIS	34	ASP	1mso	B	10
P02042	ALA	23	GLU	1shr	B	22
P02042	ALA	28	SER	1shr	D	27
P02042	ARG	117	HIS	1shr	D	116
P02042	ASN	13	LYS	1shr	B	12
P02042	GLN	126	GLU	1shr	B	125
P02042	GLU	122	VAL	1shr	B	121
P02042	GLU	27	ASP	1shr	B	26
P02042	GLU	44	GLY	1shr	B	43
P02042	GLU	44	LYS	1shr	B	43
P02042	GLU	91	VAL	1shr	D	90
P02042	HIS	147	ARG	1shr	D	146
P02042	HIS	3	ARG	1shr	B	2
P02042	LEU	76	VAL	1shr	B	75
P02042	PRO	52	ARG	1shr	D	51
P02042	VAL	21	GLU	1shr	D	20
P02647	GLU	222	LYS	2a01	A	198
P02649	CYS	130	ARG	1gs9	A	112
P02675	ARG	478	LYS	1fzc	E	448
P02679	ASP	356	VAL	2fib	A	330
P02766	ALA	129	VAL	1f86	B	109
P02766	ARG	124	HIS	1f86	A	104
P02766	ILE	88	LEU	1f86	B	68
P02768	ALA	344	THR	1n5u	A	320
P02768	ASN	342	LYS	1n5u	A	318
P02768	ASP	574	GLY	1n5u	A	550
P02768	ASP	587	ASN	1n5u	A	563
P02768	GLN	604	LYS	1n5u	A	580
P02768	GLU	106	LYS	1n5u	A	82
P02768	GLU	345	LYS	1n5u	A	321
P02768	GLU	382	LYS	1n5u	A	358
P02768	GLU	400	LYS	1n5u	A	376
P02768	GLU	406	LYS	1n5u	A	382
P02768	GLU	529	LYS	1n5u	A	505
P02768	HIS	27	TYR	1n5u	A	3
P02768	LYS	249	GLN	1n5u	A	225
P02768	LYS	565	GLU	1n5u	A	541
P02768	LYS	598	ASN	1n5u	A	574
P02787	GLU	394	LYS	2hav	A	375
P02787	GLY	277	ASP	1ryo	A	258
P02787	GLY	277	SER	1ryo	A	258
P02787	GLY	671	GLU	2hav	A	652
P02787	LYS	646	GLU	2hav	B	627
P02787	PRO	589	SER	2hav	A	570
P04070	ARG	220	GLN	1aut	C	24
P04070	ARG	220	TRP	1aut	C	24
P04156	ASN	171	SER	1i4m	A	171
P04424	ARG	379	CYS	1k62	A	379
P04424	ARG	95	CYS	1k62	B	95
P05543	TYR	329	PHE	2ceo	B	309
P06132	ARG	292	GLY	1r3s	A	292
P06132	ARG	332	HIS	1r3s	A	332
P06132	LEU	195	PHE	1r3s	A	195
P06280	GLN	279	GLU	1r46	B	279
P06280	GLY	328	ALA	1r46	B	328
P06280	GLY	361	ARG	1r46	B	361
P06280	MET	296	ILE	1r46	A	296
P06280	MET	296	VAL	1r46	A	296
P06280	PRO	146	SER	1r46	A	146
P06280	SER	65	THR	1r46	B	65
P06280	THR	410	ALA	1r46	A	410
P06737	VAL	222	ILE	2ati	B	221
P06744	ASP	539	ASN	1iat	A	538
P06865	ARG	504	CYS	2gjx	A	504
P07477	ARG	122	HIS	1trn	B	117
P07477	ASN	54	SER	1trn	A	48
P07477	GLU	79	LYS	1trn	B	74
P07686	ALA	543	THR	1now	A	543
P07686	TYR	456	SER	1now	A	456
P07741	MET	136	THR	1zn8	A	136
P08581	LYS	1244	ARG	1r0p	A	1244
P08581	VAL	1220	ILE	1r0p	A	1220
P09622	GLU	375	LYS	1zmd	F	340
P09622	ILE	393	THR	1zmd	E	358
P10746	ALA	66	VAL	1jr2	A	66
P10746	CYS	73	ARG	1jr2	A	73
P10746	PRO	53	LEU	1jr2	B	53
P10827	SER	377	LEU	1nav	A	377
P11413	ARG	227	GLN	2bh9	A	227
P11413	ARG	285	HIS	2bh9	A	285
P11413	ARG	387	HIS	2bh9	A	387
P11413	ARG	393	HIS	2bh9	A	393
P11413	ARG	454	HIS	2bh9	A	454
P11413	ARG	459	LEU	2bh9	A	459
P11413	ASN	126	ASP	2bh9	A	126
P11413	ASP	58	ASN	2bh9	A	58
P11413	GLU	156	LYS	2bh9	A	156
P11413	GLU	317	LYS	2bh9	A	317
P11413	GLY	410	CYS	2bh9	A	410
P11413	ILE	48	THR	2bh9	A	48
P11413	LEU	323	PRO	2bh9	A	323
P11413	LEU	342	PHE	2bh9	A	342
P11413	LYS	386	GLU	2bh9	A	386
P11413	PHE	173	LEU	2bh9	A	173
P11413	PHE	216	LEU	2bh9	A	216
P11413	PRO	467	ARG	2bh9	A	467
P11413	VAL	213	LEU	2bh9	A	213
P11413	VAL	394	LEU	2bh9	A	394
P13569	ASP	648	VAL	2bbs	B	648
P13716	LYS	59	ASN	1pv8	B	59
P18440	VAL	149	ILE	2ija	A	149
P19429	LYS	178	GLU	1j1e	F	178
P19429	PRO	82	SER	1j1d	F	82
P19971	ARG	44	GLN	1uou	A	44
P21549	GLY	170	ARG	1h0c	A	170
P21802	ALA	315	SER	1ev2	F	315
P21802	PRO	253	SER	1ev2	E	253
P22830	MET	267	ILE	1hrk	A	267
P22830	PHE	417	SER	1hrk	B	417
P22830	PRO	409	SER	1hrk	B	409
P30566	ARG	190	GLN	2j91	D	190
P30613	ARG	479	HIS	1liu	C	479
P30613	ARG	510	GLN	1liu	C	510
P30793	ALA	196	SER	1fb1	C	196
P30793	ARG	184	HIS	1fb1	B	184
P30793	ARG	249	SER	1fb1	D	249
P30793	LYS	224	ARG	1fb1	B	224
P30793	MET	221	THR	1fb1	C	221
P31939	LYS	426	ARG	1pkx	D	426
P35520	ALA	114	VAL	1jbq	B	114
P35520	ARG	266	LYS	1jbq	C	266
P36551	HIS	295	ASP	2aex	A	295
P36888	ASP	835	VAL	1rjb	A	835
P36959	PHE	256	ILE	2ble	A	256
P38117	ARG	164	GLN	1efv	B	164
P48637	ARG	164	GLN	2hgs	A	164
P51570	ALA	198	VAL	1wuu	C	198
P51580	ARG	215	HIS	2bzg	A	215
P60174	GLU	105	ASP	1wyi	A	104
P60174	GLY	123	ARG	1wyi	B	122
P60174	ILE	171	VAL	1wyi	B	170
P60174	PHE	241	LEU	1wyi	B	240
P60484	VAL	217	ILE	1d5r	A	217
P60891	ALA	190	VAL	2hcr	A	190
P60891	ASP	52	HIS	2hcr	A	52
P68871	ALA	11	ASP	1ird	B	210
P68871	ALA	11	VAL	1ird	B	210
P68871	ALA	129	VAL	1ird	B	328
P68871	ALA	130	ASP	1ird	B	329
P68871	ALA	130	GLU	1ird	B	329
P68871	ALA	130	VAL	1ird	B	329
P68871	ALA	136	GLU	1ird	B	335
P68871	ALA	139	THR	1ird	B	338
P68871	ALA	14	ASP	1ird	B	213
P68871	ALA	28	SER	1ird	B	227
P68871	ALA	77	ASP	1ird	B	276
P68871	ARG	105	THR	1ird	B	304
P68871	ARG	31	SER	1ird	B	230
P68871	ARG	41	LYS	1ird	B	240
P68871	ASN	103	SER	1ird	B	302
P68871	ASN	109	ASP	1ird	B	308
P68871	ASN	109	LYS	1ird	B	308
P68871	ASN	140	ASP	1ird	B	339
P68871	ASN	140	THR	1ird	B	339
P68871	ASN	20	ASP	1ird	B	219
P68871	ASN	20	LYS	1ird	B	219
P68871	ASN	20	SER	1ird	B	219
P68871	ASN	81	LYS	1ird	B	280
P68871	ASP	100	ASN	1ird	B	299
P68871	ASP	22	ASN	1ird	B	221
P68871	ASP	22	GLY	1ird	B	221
P68871	ASP	22	HIS	1ird	B	221
P68871	ASP	48	ASN	1ird	B	247
P68871	ASP	48	GLY	1ird	B	247
P68871	ASP	53	ALA	1ird	B	252
P68871	ASP	53	ASN	1ird	B	252
P68871	ASP	53	GLY	1ird	B	252
P68871	ASP	53	HIS	1ird	B	252
P68871	ASP	74	ASN	1ird	B	273
P68871	ASP	74	VAL	1ird	B	273
P68871	ASP	80	ASN	1ird	B	279
P68871	ASP	80	GLY	1ird	B	279
P68871	ASP	80	HIS	1ird	B	279
P68871	ASP	95	ASN	1ird	B	294
P68871	ASP	95	GLY	1ird	B	294
P68871	ASP	95	HIS	1ird	B	294
P68871	CYS	113	ARG	1ird	B	312
P68871	GLN	128	ARG	1ird	B	327
P68871	GLN	132	GLU	1ird	B	331
P68871	GLN	132	HIS	1ird	B	331
P68871	GLN	132	LYS	1ird	B	331
P68871	GLN	40	ARG	1ird	B	239
P68871	GLN	40	GLU	1ird	B	239
P68871	GLN	40	LYS	1ird	B	239
P68871	GLU	102	ASP	1ird	B	301
P68871	GLU	102	GLN	1ird	B	301
P68871	GLU	102	GLY	1ird	B	301
P68871	GLU	122	ALA	1ird	B	321
P68871	GLU	122	GLN	1ird	B	321
P68871	GLU	122	GLY	1ird	B	321
P68871	GLU	122	LYS	1ird	B	321
P68871	GLU	122	VAL	1ird	B	321
P68871	GLU	23	ALA	1ird	B	222
P68871	GLU	23	GLN	1ird	B	222
P68871	GLU	23	GLY	1ird	B	222
P68871	GLU	23	LYS	1ird	B	222
P68871	GLU	23	VAL	1ird	B	222
P68871	GLU	27	ALA	1ird	B	226
P68871	GLU	27	LYS	1ird	B	226
P68871	GLU	44	ALA	1ird	B	243
P68871	GLU	44	GLN	1ird	B	243
P68871	GLU	7	ALA	1ird	B	206
P68871	GLU	7	GLN	1ird	B	206
P68871	GLU	7	LYS	1ird	B	206
P68871	GLU	7	VAL	1ird	B	206
P68871	GLU	8	GLY	1ird	B	207
P68871	GLU	8	LYS	1ird	B	207
P68871	GLU	91	GLY	1ird	B	290
P68871	GLU	91	LYS	1ird	B	290
P68871	GLY	120	ALA	1ird	B	319
P68871	GLY	120	VAL	1ird	B	319
P68871	GLY	17	ASP	1ird	B	216
P68871	GLY	25	VAL	1ird	B	224
P68871	GLY	26	ARG	1ird	B	225
P68871	GLY	30	ASP	1ird	B	229
P68871	GLY	30	SER	1ird	B	229
P68871	GLY	57	ASP	1ird	B	256
P68871	GLY	65	ALA	1ird	B	264
P68871	GLY	70	ARG	1ird	B	269
P68871	GLY	70	ASP	1ird	B	269
P68871	GLY	70	SER	1ird	B	269
P68871	GLY	84	ASP	1ird	B	283
P68871	HIS	117	GLN	1ird	B	316
P68871	HIS	118	ARG	1ird	B	317
P68871	HIS	144	ARG	1ird	B	343
P68871	HIS	144	GLN	1ird	B	343
P68871	HIS	3	GLN	1ird	B	202
P68871	HIS	3	LEU	1ird	B	202
P68871	HIS	3	PRO	1ird	B	202
P68871	HIS	78	ASP	1ird	B	277
P68871	HIS	98	ASN	1ird	B	297
P68871	LEU	115	MET	1ird	B	314
P68871	LEU	29	MET	1ird	B	228
P68871	LEU	33	VAL	1ird	B	232
P68871	LEU	69	PHE	1ird	B	268
P68871	LEU	92	ARG	1ird	B	291
P68871	LYS	121	ASN	1ird	B	320
P68871	LYS	121	GLN	1ird	B	320
P68871	LYS	121	GLU	1ird	B	320
P68871	LYS	145	ASN	1ird	B	344
P68871	LYS	145	GLU	1ird	B	344
P68871	LYS	18	ASN	1ird	B	217
P68871	LYS	18	GLN	1ird	B	217
P68871	LYS	60	ASN	1ird	B	259
P68871	LYS	60	GLU	1ird	B	259
P68871	LYS	60	THR	1ird	B	259
P68871	LYS	62	GLN	1ird	B	261
P68871	LYS	66	ASN	1ird	B	265
P68871	LYS	66	GLN	1ird	B	265
P68871	LYS	67	THR	1ird	B	266
P68871	LYS	83	GLU	1ird	B	282
P68871	LYS	83	MET	1ird	B	282
P68871	LYS	9	ARG	1ird	B	208
P68871	LYS	9	ASN	1ird	B	208
P68871	LYS	9	GLU	1ird	B	208
P68871	LYS	96	ASP	1ird	B	295
P68871	LYS	96	GLU	1ird	B	295
P68871	MET	56	LYS	1ird	B	255
P68871	PHE	119	TYR	1ird	B	318
P68871	PHE	123	LEU	1ird	B	322
P68871	PHE	42	TYR	1ird	B	241
P68871	PRO	125	LEU	1ird	B	324
P68871	PRO	52	SER	1ird	B	251
P68871	PRO	6	SER	1ird	B	205
P68871	SER	50	CYS	1ird	B	249
P68871	SER	50	PHE	1ird	B	249
P68871	THR	124	ASN	1ird	B	323
P68871	THR	51	LYS	1ird	B	250
P68871	THR	85	ALA	1ird	B	284
P68871	THR	88	LYS	1ird	B	287
P68871	THR	88	PRO	1ird	B	287
P68871	TYR	36	PHE	1ird	B	235
P68871	VAL	110	LEU	1ird	B	309
P68871	VAL	110	MET	1ird	B	309
P68871	VAL	112	LEU	1ird	B	311
P68871	VAL	114	GLU	1ird	B	313
P68871	VAL	12	ILE	1ird	B	211
P68871	VAL	127	ALA	1ird	B	326
P68871	VAL	127	GLU	1ird	B	326
P68871	VAL	127	LEU	1ird	B	326
P68871	VAL	134	LEU	1ird	B	333
P68871	VAL	135	ALA	1ird	B	334
P68871	VAL	135	GLU	1ird	B	334
P68871	VAL	19	MET	1ird	B	218
P68871	VAL	2	ALA	1ird	B	201
P68871	VAL	2	GLY	1ird	B	201
P68871	VAL	21	GLU	1ird	B	220
P68871	VAL	21	MET	1ird	B	220
P68871	VAL	24	ALA	1ird	B	223
P68871	VAL	24	ASP	1ird	B	223
P68871	VAL	24	ILE	1ird	B	223
P68871	VAL	24	PHE	1ird	B	223
P69891	ALA	137	GLY	1i3d	B	136
P69892	ASP	81	ASN	1fdh	G	80
P69892	HIS	118	ARG	1fdh	G	117
P69892	LYS	67	ARG	1fdh	G	66
P69892	THR	13	ARG	1fdh	G	12
P69905	ALA	112	THR	1ird	A	111
P69905	ALA	112	VAL	1ird	A	111
P69905	ALA	116	ASP	1ird	A	115
P69905	ALA	121	GLU	1ird	A	120
P69905	ALA	124	SER	1ird	A	123
P69905	ALA	13	ASP	1ird	A	12
P69905	ALA	131	ASP	1ird	A	130
P69905	ALA	20	ASP	1ird	A	19
P69905	ALA	20	GLU	1ird	A	19
P69905	ALA	22	PRO	1ird	A	21
P69905	ALA	27	GLU	1ird	A	26
P69905	ALA	27	VAL	1ird	A	26
P69905	ALA	54	ASP	1ird	A	53
P69905	ALA	6	ASP	1ird	A	5
P69905	ALA	6	PRO	1ird	A	5
P69905	ALA	66	THR	1ird	A	65
P69905	ALA	70	THR	1ird	A	69
P69905	ALA	72	GLU	1ird	A	71
P69905	ALA	72	VAL	1ird	A	71
P69905	ALA	80	GLY	1ird	A	79
P69905	ALA	80	THR	1ird	A	79
P69905	ALA	83	ASP	1ird	A	82
P69905	ALA	89	SER	1ird	A	88
P69905	ARG	142	HIS	1ird	A	141
P69905	ARG	93	GLN	1ird	A	92
P69905	ARG	93	LEU	1ird	A	92
P69905	ASN	69	ASP	1ird	A	68
P69905	ASN	69	LYS	1ird	A	68
P69905	ASN	79	ASP	1ird	A	78
P69905	ASN	79	HIS	1ird	A	78
P69905	ASN	79	LYS	1ird	A	78
P69905	ASP	127	TYR	1ird	A	126
P69905	ASP	48	ALA	1ird	A	47
P69905	ASP	48	ASN	1ird	A	47
P69905	ASP	48	GLY	1ird	A	47
P69905	ASP	65	ASN	1ird	A	64
P69905	ASP	65	GLY	1ird	A	64
P69905	ASP	65	HIS	1ird	A	64
P69905	ASP	7	ASN	1ird	A	6
P69905	ASP	75	ASN	1ird	A	74
P69905	ASP	75	HIS	1ird	A	74
P69905	ASP	76	ALA	1ird	A	75
P69905	ASP	76	ASN	1ird	A	75
P69905	ASP	76	HIS	1ird	A	75
P69905	ASP	86	ASN	1ird	A	85
P69905	ASP	86	VAL	1ird	A	85
P69905	ASP	95	ASN	1ird	A	94
P69905	GLN	55	ARG	1ird	A	54
P69905	GLN	55	GLU	1ird	A	54
P69905	GLU	117	ALA	1ird	A	116
P69905	GLU	117	GLN	1ird	A	116
P69905	GLU	117	LYS	1ird	A	116
P69905	GLU	24	ASP	1ird	A	23
P69905	GLU	24	GLN	1ird	A	23
P69905	GLU	24	LYS	1ird	A	23
P69905	GLU	24	VAL	1ird	A	23
P69905	GLU	28	ASP	1ird	A	27
P69905	GLU	31	GLN	1ird	A	30
P69905	GLY	16	ASP	1ird	A	15
P69905	GLY	19	ARG	1ird	A	18
P69905	GLY	19	ASP	1ird	A	18
P69905	GLY	23	ASP	1ird	A	22
P69905	GLY	52	ASP	1ird	A	51
P69905	GLY	52	SER	1ird	A	51
P69905	GLY	58	ARG	1ird	A	57
P69905	GLY	58	ASP	1ird	A	57
P69905	HIS	104	TYR	1ird	A	103
P69905	HIS	113	ARG	1ird	A	112
P69905	HIS	123	GLN	1ird	A	122
P69905	HIS	21	ARG	1ird	A	20
P69905	HIS	21	GLN	1ird	A	20
P69905	HIS	46	ASP	1ird	A	45
P69905	HIS	46	GLN	1ird	A	45
P69905	HIS	51	ARG	1ird	A	50
P69905	HIS	59	GLN	1ird	A	58
P69905	HIS	73	ARG	1ird	A	72
P69905	HIS	90	ARG	1ird	A	89
P69905	HIS	90	GLN	1ird	A	89
P69905	HIS	90	TYR	1ird	A	89
P69905	LEU	114	ARG	1ird	A	113
P69905	LEU	114	HIS	1ird	A	113
P69905	LEU	137	MET	1ird	A	136
P69905	LEU	35	ARG	1ird	A	34
P69905	LYS	100	GLU	1ird	A	99
P69905	LYS	12	ASN	1ird	A	11
P69905	LYS	12	GLN	1ird	A	11
P69905	LYS	12	GLU	1ird	A	11
P69905	LYS	140	THR	1ird	A	139
P69905	LYS	57	ARG	1ird	A	56
P69905	LYS	57	ASN	1ird	A	56
P69905	LYS	61	GLU	1ird	A	60
P69905	LYS	62	ASN	1ird	A	61
P69905	LYS	62	THR	1ird	A	61
P69905	LYS	8	GLU	1ird	A	7
P69905	LYS	91	ARG	1ird	A	90
P69905	LYS	91	ASN	1ird	A	90
P69905	LYS	91	THR	1ird	A	90
P69905	MET	1	THR	1bab	A	1
P69905	MET	1	VAL	1bab	A	1
P69905	PRO	115	ARG	1ird	A	114
P69905	PRO	115	SER	1ird	A	114
P69905	PRO	78	HIS	1ird	A	77
P69905	SER	82	CYS	1ird	A	81
P69905	THR	42	SER	1ird	A	41
P69905	TYR	25	HIS	1ird	A	24
P69905	VAL	122	MET	1ird	A	121
P69905	VAL	136	GLU	1ird	A	135
P69905	VAL	2	GLU	1ird	A	1
P69905	VAL	2	GLY	1ird	A	1
P69905	VAL	56	LEU	1ird	A	55
Q03518	ASP	637	GLY	1jj7	A	637
Q13867	ILE	443	VAL	2cb5	A	443
Q14376	ASN	34	SER	1ek6	B	34
Q14376	LYS	257	ARG	1ek6	A	257
Q99714	ARG	130	CYS	1u7t	B	130
Q9BZR6	ARG	196	HIS	1ozn	A	196

CPDs - Supporting Material

CPD Mutations with structures