Servers

Most of the servers we provide are linked to from other parts of the site, but this page summarizes the links to those and also includes some other facilities that we make available.

Follow the tabs above, or the links below to access the various servers.

Antibodies

Analysis of antibody sequence and structure

KabatMan Point-and-click interface to KabatMan
KabatMan Full query interface to KabatMan
SeqTest Check your antibody sequence for unusual features
Chothia Canonicals Identify canonical conformations for CDRs for your antibody sequence
Human subgroups Identify subgroups for your human antibody sequence
SHAB Assess humanness of an antibody sequence
SACS Automatically maintained database of antibody structures in the PDB
AbNum Automatically apply numbering to an antibody sequence

Mutations

Analysis of structural and disease effects of mutations

CheckHBond Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility. Can be used when examining mutations to see whether hydrogen bonds are maintained
SAAP Database Query our database of SNP data
G6PD Database Query our database of mutations in G6PD
OMIM Missense Mutations Query our database of missense mutations extracted from OMIM with validated residue numbers of mutations sites in SwissProt

Protein structure and sequence

Tools for analysis of protein structure (rapid structure comparison, mappings to UniProt and EC numbers, analysis of hydrogen bonds) and sequence (orthologous groups, annotation)

FOSTA Database of functionally-equivalent proteins, i.e. groups of orthologous proteins extracted from SwissProt which perform the same function in different species. (This is the new name for Orthofind.)
CheckHBond Evaluate whether a pair of residues can form a hydrogen bond taking into account sidechain flexibility
PDBSprotEC Link PDB protein chains to SwissProt entries and EC numbers
PDBSWS Comprehensive mapping of PDB protein chains to SwissProt entries
TopScan Rapid approximate comparison of a structure against structures in the PDB
APAT Automated Protein Annotation Tool

Miscellaneous

Other tools

PubMed Tools for PubMed literature searching

Availability - IMPORTANT

Our web site is at risk on Wednesday 10th and 17th September between 4 and 6pm
This is for work on departmental servers

18 July 2008 RSS Newsfeed

We now have an RSS Newsfeed where announcements about software, server and database updates will appear.

15 July 2008 ImPACT

ImPACT now uses Muscle for alignments. Species similarity data have also been updated.

9 May 2008 PDBSprotEC

PDBSprotEC now contains many more mappings as EC numbers are now gathered from trEMBL as well as from SwissProt. Links to external servers have also been fixed.