ProFit

Description

ProFit is designed to be the ultimate protein least squares fitting program. It has many features including flexible specification of fitting zones and atoms, calculation of RMS over different zones or atoms, RMS-by-residue calculation, on-line help facility, etc.

Some comments from users:

A user from Cambridge
Just downloaded ProFit on the recommendation of a collegue and got the answer I wanted within 5 minutes, what a fantastic program, easy to 'install' and elegant and simple syntax (can you tell I'm not used to this!!!).

A user from Los Alamos
Following the instructions in the on-line documentation, I was able to quickly compute the rmsd between structures in two pdb files.... Thank you for offering this program for use by the research community.

A user from the University of Chicago
Thanks a lot for writing such an useful piece of software and more importantly for documenting it and providing it for our use.

You can read the README file before downloading.

Documentation

You can read the Full ProFit documentation online or as a PDF file.

FAQs and notes

Here is a list of general frequently asked questions.

Important warning about using HETATMs and changes in ProFitV2.2!

Download

ProFit is freely available for use by not-for-profit organisations and for commercial organisations (providing they inform the author that they are using it). It may not be distributed without the author's permission, but must be obtained from this site. It is supplied as a gzipped tar file of source code and as an Linux binary.

Bernhard Rupp has kindly provided a ZIP file of ProFit compiled for Windows (Win32). This is only available for Version 2.3 of ProFit.

Updates

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Acknowledgements

Development of V2.6 performed by Dr. Craig T. Porter has been funded by the BBSRC.